SCHEMBL344590

SCHEMBL344590

Fc1cc(F)c(CBr)cc1F

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 5/20 0.46
HDAC1 Q13547 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18226969 0.94 DPP4 (0.39) DPP4
SCHEMBL4826854 0.88 DPP4 (0.39) DPP4
SCHEMBL30149683 0.88 DPP4 (0.39) DPP4
SCHEMBL30441973 0.81 DPP4 (0.33) DPP4
SCHEMBL29545980 0.81 KDM1A (0.41) DPP4
SCHEMBL377065 0.81 KDM1A (0.41) DPP4
SCHEMBL16860902 0.81 DPP4 (0.33) DPP4
SCHEMBL1262764 0.81 DPP4 (0.33) DPP4
SCHEMBL19433173 0.79 DPP4 (0.36) DPP4
SCHEMBL693457 0.79 GPR84 (0.37) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119465288-A Anion exchange membrane, preparation method and application thereof, and electrolysis device 氢和元泰(常州)新材料科技有限公司 2025-02-18 CN claimed
CN-114605223-B Method for preparing 2,4, 5-trifluoro-benzyl bromide by using 2,4, 5-trifluoro-benzyl chloride 浙江永太科技股份有限公司 2024-03-15 CN claimed
CN-220496319-U 2,4, 5-trifluoro benzyl bromide production system 宁夏华昊生物科技有限公司 2024-02-20 CN claimed
CN-114805314-B Synthesis method of Entecavir 杭州国瑞生物科技有限公司 2023-12-15 CN claimed
WO-2023201802-A1 SYNTHESIS METHOD FOR ENSITRELVIR 杭州国瑞生物科技有限公司 2023-10-26 WO claimed
CN-116924884-A Preparation method of 2,4, 5-trifluoro-benzyl bromide 安庆朗坤药业有限公司 2023-10-24 CN claimed
CN-114644621-B Preparation method of oral medicine S-217622 for treating new coronaries pneumonia 苏州立新制药有限公司 2023-08-22 CN claimed
CN-114853560-B Preparation method of 2,4, 5-trifluoro-benzyl bromide and 2,4, 5-trifluoro-benzoic acid 湖南复瑞生物医药技术有限责任公司 2023-04-21 CN claimed
CN-114853560-A Preparation method of 2,4, 5-trifluorobenzyl bromide and 2,4, 5-trifluorobenzoic acid 湖南复瑞生物医药技术有限责任公司 2022-08-05 CN claimed
CN-114805314-A Synthesis method of Ensaitevir 杭州国瑞生物科技有限公司 2022-07-29 CN claimed
CN-114773149-A Efficient synthesis method of medicine intermediate 2,4, 5-trifluorobromobenzyl 浙江解氏新材料股份有限公司 2022-07-22 CN claimed
CN-114773147-A Preparation method of 2,4, 5-trifluorobenzyl bromide 浙江永太科技股份有限公司 2022-07-22 CN claimed
CN-114644621-A Preparation method of oral medicine S-217622 for treating neocoronary pneumonia 苏州立新制药有限公司 2022-06-21 CN claimed
CN-114605223-A Method for preparing 2,4, 5-trifluorobenzyl bromide by using 2,4, 5-trifluorobenzyl chloride 浙江永太科技股份有限公司 2022-06-10 CN claimed
CN-114591141-A Preparation method of 2,4, 5-trifluorobenzyl bromide 浙江永太科技股份有限公司 2022-06-07 CN claimed
CN-108314688-B A kind of synthetic method of sitagliptin 安徽海康药业有限责任公司 2019-08-06 CN claimed
CN-108314688-A A kind of synthetic method of sitagliptin 安徽海康药业有限责任公司 2018-07-24 CN claimed
CN-104987338-A Low cost method for preparing sitagliptin phosphate salt key intermediate XINFA PHARMACEUTICAL CO LTD 2015-10-21 CN claimed
US-20260125365-A1 TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME SHIONOGI & CO., LTD. (JP) 2026-05-07 US disclosed
CN-1079962-A New substituted tertiary amine compound and salt thereof YAMANOUCHI PHARMA CO LTD (JP) 1993-12-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125365-A1 TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ACE2, ACE, SARS1 DPP4 6/4885HDAC1 120/4885HDAC8 720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.