Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.56 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.50 |
| ▸ | F13A1 | P00488 | 2/20 | 0.50 |
| ▸ | TGM2 | P21980 | 2/20 | 0.50 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32681272 | 0.91 | DPP3 (0.62) | DPP3NTSR2NTSR1SORT1CAPN1 | |
| SCHEMBL30093405 | 0.88 | F13A1 (0.58) | DPP3NTSR2NTSR1SORT1CAPN1 | |
| SCHEMBL29713766 | 0.88 | DPP3 (0.63) | DPP3NTSR2NTSR1SORT1CAPN1 | |
| SCHEMBL30209475 | 0.88 | DPP3 (0.55) | DPP3NTSR2NTSR1SORT1CAPN1 | |
| SCHEMBL29555002 | 0.87 | CAPN1 (0.54) | DPP3CAPN1CTSBCALCRLCXCR4 | |
| SCHEMBL32681280 | 0.86 | DPP3 (0.59) | DPP3NTSR2NTSR1SORT1CAPN1 | |
| SCHEMBL30051283 | 0.86 | DPP3 (0.61) | DPP3NTSR2NTSR1SORT1CAPN1 | |
| SCHEMBL1027785 | 0.86 | CAPN1 (0.53) | DPP3NTSR2NTSR1SORT1CAPN1 | |
| SCHEMBL30633418 | 0.86 | DPP3 (0.60) | DPP3CAPN1CTSBKISS1RCXCR4 | |
| SCHEMBL30224116 | 0.86 | CAPN1 (0.64) | DPP3NTSR2NTSR1SORT1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116726183-A | Compositions and methods for treating cancers associated with ETBR activation | ENB治疗公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-108025035-B | Compositions and methods for treating cancers associated with ETBR activation | ENB治疗公司 | 2023-06-13 | — | — | CN | disclosed |