Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 2/20 | 0.46 |
| ▸ | TGM2 | P21980 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30442994 | 0.86 | DPP3 (0.56) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL31326864 | 0.83 | DPP3 (0.56) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL30093405 | 0.83 | F13A1 (0.58) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL2195872 | 0.82 | DPP4 (0.58) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL29713766 | 0.82 | DPP3 (0.63) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL30974182 | 0.81 | NTSR2 (0.70) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL2183131 | 0.81 | DPP4 (0.62) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL29974614 | 0.81 | DPP3 (0.63) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL30679614 | 0.81 | CAPN1 (0.55) | CAPN1CTSBNTSR2NTSR1SORT1 | |
| SCHEMBL30051283 | 0.80 | DPP3 (0.61) | CAPN1CTSBNTSR2NTSR1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246062-B1 | Methods and compositions for emergency contraception using endothelin receptor antagonists | POPULATION COUNCIL INC (US) | 2012-09-26 | — | — | EP | disclosed |
| EP-1906987-B1 | METHODS AND COMPOSITIONS FOR EMERGENCY CONTRACEPTION USING ENDOTHELIN RECEPTOR ANTAGONISTS | POPULATION COUNCIL INC (US) | 2011-01-19 | — | — | EP | disclosed |
| EP-2246062-A1 | Methods and compositions for emergency contraception using endothelin receptor antagonists | THE POPULATION COUNCIL, INC. (US) | 2010-11-03 | — | — | EP | disclosed |