SCHEMBL30443501

SCHEMBL30443501

CC(C)(C)OC(=O)N1C[C@@H]2CN(C(=O)c3c(F)cccc3-n3nccn3)C[C@@H]2C1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 20/20 0.63
HCRTR2 O43614 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27056184 1.00 HCRTR1 (0.63) HCRTR1HCRTR2
SCHEMBL1671087 1.00 HCRTR1 (0.63) HCRTR1HCRTR2
SCHEMBL17793770 0.87 HCRTR1 (0.52) HCRTR1HCRTR2
SCHEMBL19345643 0.84 HCRTR1 (0.70) HCRTR1HCRTR2
SCHEMBL27056148 0.84 HCRTR1 (0.47) HCRTR1HCRTR2
SCHEMBL11907815 0.83 HCRTR1 (0.56) HCRTR1HCRTR2
SCHEMBL30465902 0.83 HCRTR1 (0.54) HCRTR1HCRTR2
SCHEMBL11907807 0.83 HCRTR1 (0.56) HCRTR1HCRTR2
SCHEMBL27029922 0.83 HCRTR1 (0.71) HCRTR1HCRTR2
SCHEMBL1586869 0.83 HCRTR1 (0.59) HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4588921-A1 FREE BASE CRYSTAL FORM OF POLYCYCLIC COMPOUND OF NITROGEN-CONTAINING HETEROCYCLE, AND PREPARATION METHOD THEREFOR Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) 2025-07-23 EP disclosed
CN-116217593-B Octahydropyrrolo [3,4-c ] pyrrole methyl ketone derivative and application thereof 江苏恩华药业股份有限公司 2025-05-09 CN disclosed
CN-119866339-A Free base crystalline forms of nitrogen-containing heterocyclic polycyclic compounds and methods of making the same 江苏豪森药业集团有限公司 2025-04-22 CN disclosed
US-20240208981-A1 NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2024-06-27 US disclosed
CN-117700416-A Salts of polycyclic compounds containing nitrogen heterocycles and process for preparing the same 江苏豪森药业集团有限公司 2024-03-15 CN disclosed
EP-4310089-A1 NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2024-01-24 EP disclosed
CN-116981670-A Polycyclic compound containing nitrogen heterocycle, preparation method and application thereof 上海翰森生物医药科技有限公司 2023-10-31 CN disclosed
CN-116217593-A Octahydropyrrolo [3,4-c ] pyrrole methyl ketone derivative and application thereof 江苏恩华药业股份有限公司 2023-06-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208981-A1 NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF HCRTR1, HCRTR2, CCKBR HCRTR1 1/4885HCRTR2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.