SCHEMBL3044369

SCHEMBL3044369

O=C(O)C1Nc2ccccc2N1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
GAA P10253 2/20 0.50
ALDH1A1 P00352 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
ALOX15 P16050 3/20 0.42
KDM4E B2RXH2 2/20 0.42
TP53 P04637 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42
EGFR P00533 2/20 0.40
BRPF1 P55201 1/20 0.40
CREBBP Q92793 1/20 0.40
PTPN7 P35236 2/20 0.40
HSPA1A P0DMV8 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8143860 0.83 TNKS2 (0.56) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL27404564 0.81 MAPT (0.42) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL15040698 0.80 MEN1 (0.55) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL27643153 0.78 MAPT (0.46) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL16716394 0.77 GAA (0.47) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL6429993 0.75 PTPN7 (0.61) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL3130279 0.75 GAA (0.56) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL8582807 0.75 IDO1 (0.40) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL6186463 0.72 MAPT (0.58) MAPTGAAALDH1A1MEN1KMT2A
SCHEMBL22722361 0.72 CREBBP (0.53) MAPTGAAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed
CN-117940496-A Thermoplastic polyurethane foam steering wheel cover 路博润先进材料公司 2024-04-26 CN disclosed
CN-117940472-A Steering wheel structure 路博润先进材料公司 2024-04-26 CN disclosed
WO-2023043779-A1 THERMOPLASTIC POLYURETHANE FOAM STEERING WHEEL COVER LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-03-23 WO disclosed
WO-2023043780-A1 STEERING WHEEL CONSTRUCTION LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-03-23 WO disclosed
US-11525264-B2 Silicone membranes HOLCIM TECHNOLOGY LTD (CH) 2022-12-13 US disclosed
US-20200181911-A1 SILICONE MEMBRANES HOLCIM TECHNOLOGY LTD (CH) 2020-06-11 US disclosed
US-10577801-B2 Silicone membranes FIRESTONE BUILDING PRODUCTS COMPANY, LLC (US) 2020-03-03 US disclosed
US-9896601-B2 Dirt pick-up resistant silicone compositions Gaco Western, LLC (US) 2018-02-20 US disclosed
US-20180016791-A1 SILICONE MEMBRANES AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2018-01-18 US disclosed
US-20070082990-A1 Urethane Elastomers with Improved Color Stability JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2007-04-12 US disclosed
US-7148278-B2 Urethane elastomers with improved color stability ACUSHNET COMPANY (US) 2006-12-12 US disclosed
US-6949595-B2 Multi-layer golf ball with translucent cover ACUSHNET COMPANY (US) 2005-09-27 US disclosed
US-20050148409-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2005-07-07 US disclosed
US-20040176188-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2004-09-09 US disclosed
US-20040176531-A1 Multi-layer golf ball with translucent cover JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-09-09 US disclosed
US-20040176185-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2004-09-09 US disclosed
US-20040176184-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2004-09-09 US disclosed
US-20040018895-A1 Urethane elastomers with improved color stability JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-01-29 US disclosed
US-20020086743-A1 Urethane elastomers with improved color stability ACUSHNET COMPANY 2002-07-04 US disclosed