SCHEMBL30444072

SCHEMBL30444072

CC(=O)CCCCCCC(=O)NCCc1c(-c2ccccc2)[nH]c2ccccc12

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 9/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30444068 0.91 MTNR1A (0.65) HDAC1
SCHEMBL8271509 0.90 HDAC1 (0.58) HDAC1
SCHEMBL5130952 0.89 HDAC1 (0.57) HDAC1
SCHEMBL8270879 0.88 HDAC1 (0.57) HDAC1
SCHEMBL27695329 0.86 HDAC1 (0.66) HDAC1
SCHEMBL5139597 0.84 HDAC1 (0.84) HDAC1
SCHEMBL5139594 0.84 HDAC1 (0.84) HDAC1
Hydrochloric Acid SCHEMBL5126533 0.84 HDAC1 (0.82) HDAC1
SCHEMBL5119607 0.84 HDAC1 (1.00) HDAC1
Hydrochloric Acid SCHEMBL5123169 0.84 HDAC1 (0.76) HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230094176-A1 COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS CERENO SCIENT AB (SE) 2023-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230094176-A1 COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS HDAC3, HDAC2, HDAC1 HDAC1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.