Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881298 | 0.84 | CA12 (0.47) | CA12CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL292179 | 0.84 | CA12 (0.47) | CA12CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL27218070 | 0.83 | CA12 (0.46) | CA12CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL12643972 | 0.83 | CA12 (0.46) | CA12CA9MEN1KMT2AALDH1A1 | |
| Alcohol SCHEMBL9054340 | 0.79 | ALDH1A1 (0.45) | CA12CA9KMT2AALDH1A1CHRM2 | |
| SCHEMBL22939448 | 0.79 | CA12 (0.48) | CA12CA9ALDH1A1GLSCHRM2 | |
| SCHEMBL30280109 | 0.77 | CA12 (0.44) | CA12CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL4711840 | 0.77 | CA12 (0.44) | CA12CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL6150561 | 0.77 | CA12 (0.44) | CA12CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL3727196 | 0.76 | CHRM2 (0.56) | CA12CA9ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4408847-A1 | IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2024-08-07 | — | — | EP | disclosed |
| WO-2023049887-A1 | IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | WO | disclosed |