Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 17/20 | 0.77 |
| ▸ | CTSB | P07858 | 11/20 | 0.77 |
| ▸ | CTSF | Q9UBX1 | 11/20 | 0.77 |
| ▸ | CTSS | P25774 | 2/20 | 0.60 |
| ▸ | CTSK | P43235 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765242 | 1.00 | CTSL (0.77) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL3044484 | 1.00 | CTSL (0.77) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL3044478 | 1.00 | CTSL (0.77) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL3769295 | 0.88 | CTSL (0.76) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL3769290 | 0.88 | CTSL (0.76) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL3769293 | 0.88 | CTSL (0.76) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL15254806 | 0.87 | CTSL (1.00) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL3763659 | 0.87 | CTSL (1.00) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL3762220 | 0.87 | CTSL (0.74) | CTSLCTSBCTSFCTSSCTSK | |
| SCHEMBL3762214 | 0.87 | CTSL (0.74) | CTSLCTSBCTSFCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225196-A1 | CYSTEINE PROTEASE INHIBITORS FOR THE TREATMENT OF PARASITIC DISEASES | Merck Frosst Canada Ltd. (CA) | 2010-09-08 | — | — | EP | claimed |
| WO-2009067797-A1 | CYSTEINE PROTEASE INHIBITORS FOR THE TREATMENT OF PARASITIC DISEASES | MERCK FROSST CANADA LTD. (CA) | 2009-06-04 | — | — | WO | claimed |