Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168401 | 1.00 | S1PR2 (0.35) | S1PR2TSHRCSNK1A1CLK4ALDH1A1 | |
| SCHEMBL30444608 | 0.77 | SRC (0.40) | ALDH1A1KDM4ESRCAR | |
| SCHEMBL20168042 | 0.77 | SRC (0.40) | ALDH1A1KDM4ESRCAR | |
| SCHEMBL29505699 | 0.75 | UHRF1 (0.46) | S1PR2TSHRCSNK1A1CLK4ALDH1A1 | |
| SCHEMBL317517 | 0.75 | UHRF1 (0.46) | S1PR2TSHRCSNK1A1CLK4ALDH1A1 | |
| SCHEMBL21927619 | 0.74 | EGLN2 (0.41) | S1PR2TSHRCSNK1A1CLK4ALDH1A1 | |
| SCHEMBL14068317 | 0.72 | S1PR2 (0.37) | S1PR2TSHRCSNK1A1CLK4ALDH1A1 | |
| SCHEMBL11744305 | 0.72 | S1PR2 (0.40) | S1PR2TSHRCSNK1A1CLK4ALDH1A1 | |
| SCHEMBL20642285 | 0.72 | S1PR2 (0.37) | S1PR2TSHRCSNK1A1CLK4ALDH1A1 | |
| SCHEMBL3826142 | 0.72 | S1PR2 (0.37) | S1PR2TSHRCSNK1A1CLK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139862-B | Substituted bicyclic heterocyclic derivatives useful as ROMK channel inhibitors | 百时美施贵宝公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-110678463-B | Substituted nitrogen-containing compounds | 百时美施贵宝公司 | 2023-06-06 | — | — | CN | disclosed |