SCHEMBL317517

SCHEMBL317517

Cc1cc(C)c(C#N)cn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.46
KDM4E B2RXH2 4/20 0.39
S1PR2 O95136 1/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
CSNK1A1 P48729 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
RECQL P46063 2/20 0.33
IDH1 O75874 2/20 0.33
CYP11B1 P15538 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29505699 1.00 UHRF1 (0.46) UHRF1KDM4ES1PR2TSHRMEN1
Formaldehyde SCHEMBL28191892 0.94 UHRF1 (0.42) UHRF1KDM4ES1PR2TSHRMEN1
SCHEMBL21927208 0.84 UHRF1 (0.38) UHRF1KDM4ETSHRCYP1A2CYP2A6
SCHEMBL2751008 0.82 UHRF1 (0.41) UHRF1KDM4ETSHRMEN1KMT2A
SCHEMBL21927619 0.80 EGLN2 (0.41) KDM4ES1PR2TSHRCSNK1A1CLK4
SCHEMBL3826142 0.78 S1PR2 (0.37) KDM4ES1PR2TSHRMEN1KMT2A
SCHEMBL20642285 0.78 S1PR2 (0.37) KDM4ES1PR2TSHRKMT2ACSNK1A1
SCHEMBL11744305 0.78 S1PR2 (0.40) KDM4ES1PR2TSHRCSNK1A1CLK4
SCHEMBL31750396 0.78 S1PR2 (0.46) KDM4ES1PR2TSHRKMT2ACYP1A2
SCHEMBL14068317 0.78 S1PR2 (0.37) KDM4ES1PR2TSHRKMT2ACSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115636781-A Synthesis method of 2, 4-dimethyl-5-aminopyridine 山西永津集团有限公司 2023-01-24 CN claimed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP disclosed
EP-3365339-B1 NOVEL FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2025-07-16 EP disclosed
WO-2025068710-A1 COMPOUNDS COMPRISING AN IMIDAZOLE CORE Tay Therapeutics Limited (GB) 2025-04-03 WO disclosed
CN-116813621-A 9H purine compounds, pharmaceutical composition and application thereof 江南大学 2023-09-29 CN disclosed
US-20230234970-A1 IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF ABBISKO THERAPEUTICS CO., LTD. (CN) 2023-07-27 US disclosed
CN-115636781-A Synthesis method of 2, 4-dimethyl-5-aminopyridine 山西永津集团有限公司 2023-01-24 CN disclosed
CN-115636781-A Synthesis method of 2, 4-dimethyl-5-aminopyridine 山西永津集团有限公司 2023-01-24 CN disclosed
WO-2022258023-A1 COMPOUND AS CDK KINASE INHIBITOR AND USE THEREOF 郑州同源康医药有限公司 2022-12-15 WO disclosed
US-20220363675-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2022-11-17 US disclosed
WO-2003002556-A1 NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE H. LUNDBECK A/S (DK) 2003-01-09 WO disclosed
EP-1231207-A1 NOVEL BIPYRIDYL DERIVATIVES Sankio Chemical Co., Ltd. (JP) 2002-08-14 EP disclosed
US-5821255-A REGULATING THE SECRETION OF CORTICOTROPIN, BETA-ENDORPHIN OR PEPTIDES DERIVED FROM PROOPIOMELANOCORTIN SANOFI (FR) 1998-10-13 US disclosed
EP-0659747-B1 Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them SANOFI SA (FR) 1998-04-01 EP disclosed
US-5602132-A USEFUL IN TREATMENT OF PATHOLOGIES INVOLVING CORTICOTROPIN RELEASING FACTOR SANOFI (FR) 1997-02-11 US disclosed
CN-1127252-A Branched-amino-sbustituted thiazoles, processes for their preparation and the pharmaceutical compositions which contain them SANOFI SA (FR) 1996-07-24 CN disclosed
EP-0659747-A1 Branched aminothiazole derivatives process for their preparation and pharmaceutical compositions containing them SANOFI (FR) 1995-06-28 EP disclosed
EP-0104876-B1 HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES ICI AUSTRALIA LIMITED (AU) 1991-12-27 EP disclosed
US-4631081-A Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1986-12-23 US disclosed
EP-0104876-A2 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1984-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234970-A1 IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF CD274, PDCD1, PDCD1LG2 UHRF1 1612/4885KDM4E 2535/4885S1PR2 2131/4885
US-20220363675-A1 Novel Ferroportin Inhibitors HAMP, SLC40A1, HMOX1 UHRF1 3811/4885KDM4E 4503/4885S1PR2 877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.