Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20574767 | 1.00 | KCNJ1 (0.47) | KCNJ1KDM4EMAPK1SMN1; SMN2P2RX7 | |
| SCHEMBL20168218 | 0.85 | KCNJ1 (0.45) | KCNJ1KDM4EP2RX7MEN1KMT2A | |
| SCHEMBL30444634 | 0.85 | KCNJ1 (0.45) | KCNJ1KDM4EP2RX7MEN1KMT2A | |
| SCHEMBL20176988 | 0.81 | RECQL (0.47) | KCNJ1KDM4EMAPK1SMN1; SMN2P2RX7 | |
| SCHEMBL30445572 | 0.81 | RECQL (0.47) | KCNJ1KDM4EMAPK1SMN1; SMN2P2RX7 | |
| SCHEMBL20574272 | 0.80 | KCNJ1 (0.42) | KCNJ1KDM4EMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL30445102 | 0.80 | KCNJ1 (0.42) | KCNJ1KDM4EMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL26536810 | 0.78 | KCNJ1 (0.47) | KCNJ1KDM4EP2RX7 | |
| SCHEMBL20574945 | 0.77 | P2RX7 (0.43) | KCNJ1P2RX7 | |
| SCHEMBL20575090 | 0.76 | KCNJ1 (0.48) | KCNJ1KDM4EMAPK1SMN1; SMN2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678463-B | Substituted nitrogen-containing compounds | 百时美施贵宝公司 | 2023-06-06 | — | — | CN | disclosed |