Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 14/20 | 0.47 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP9 | P55211 | 1/20 | 0.44 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 1/20 | 0.43 |
| ▸ | SCTR | P47872 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445684 | 0.94 | GLP1R (0.44) | BACE1BACE2SLC6A2GLP1R | |
| SCHEMBL30445380 | 0.87 | BACE1 (0.47) | BACE1BACE2 | |
| SCHEMBL30974127 | 0.87 | GLP1R (0.44) | BACE1BACE2IL23RGLP1RSCTR | |
| SCHEMBL30512584 | 0.87 | BACE1 (0.51) | BACE1BACE2GLP1RSCTR | |
| SCHEMBL30505408 | 0.86 | BACE1 (0.54) | BACE1BACE2CASP1CASP3CASP9 | |
| SCHEMBL29904276 | 0.86 | BACE1 (0.41) | BACE1BACE2CTSD | |
| SCHEMBL30445399 | 0.85 | CALCR (0.51) | BACE1IL23ROPRD1GLP1RSCTR | |
| SCHEMBL30445774 | 0.85 | CALCR (0.48) | BACE1BACE2GLP1RSCTR | |
| SCHEMBL30974539 | 0.85 | BACE1 (0.47) | BACE1BACE2IL23RGLP1RSCTR | |
| SCHEMBL30974314 | 0.84 | BACE1 (0.48) | BACE1BACE2OPRD1GLP1RSCTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | claimed |
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | disclosed |