Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 17/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.54 |
| ▸ | CTSD | P07339 | 2/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | NPY4R | P50391 | 1/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31738233 | 0.88 | IL1RN (0.45) | BACE1BACE2NPY1RNPY2RNPY4R | |
| SCHEMBL31513110 | 0.88 | NPY1R (0.52) | BACE1BACE2CTSDNPY1RNPY2R | |
| SCHEMBL29416052 | 0.87 | BACE1 (0.55) | BACE1BACE2CTSD | |
| SCHEMBL5699005 | 0.87 | BACE1 (0.49) | BACE1BACE2CTSDNPY1RNPY2R | |
| SCHEMBL5699001 | 0.87 | BACE1 (0.49) | BACE1BACE2CTSDNPY1RNPY2R | |
| SCHEMBL30536319 | 0.87 | F2 (0.46) | BACE1 | |
| SCHEMBL7163139 | 0.87 | BACE1 (0.42) | BACE1BACE2CTSDIL1RNERAP2 | |
| SCHEMBL7163147 | 0.87 | BACE1 (0.42) | BACE1BACE2CTSDIL1RNERAP2 | |
| SCHEMBL30445172 | 0.86 | BACE1 (0.47) | BACE1BACE2CTSDCASP1CASP3 | |
| SCHEMBL31020880 | 0.86 | NPY1R (0.49) | BACE1BACE2NPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195857-B | Antihypertensive peptide and preparation method and application thereof | 中国科学院海洋研究所 | 2023-07-04 | — | — | CN | claimed |
| CN-114195857-B | Antihypertensive peptide and preparation method and application thereof | 中国科学院海洋研究所 | 2023-07-04 | — | — | CN | disclosed |