Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | ROS1 | P08922 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | MARK3 | P27448 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24272080 | 1.00 | MAPT (0.45) | MAPTKDM4ECDC7PLK4DYRK3 | |
| SCHEMBL30445722 | 0.81 | BPGM (0.58) | MAPTKDM4ECDC7PLK4DYRK3 | |
| SCHEMBL24348503 | 0.81 | BPGM (0.58) | MAPTKDM4ECDC7PLK4DYRK3 | |
| SCHEMBL30445770 | 0.80 | BPGM (0.55) | MAPTKDM4ECDC7PLK4DYRK3 | |
| SCHEMBL24271884 | 0.80 | BPGM (0.55) | MAPTKDM4ECDC7PLK4DYRK3 | |
| SCHEMBL26704457 | 0.78 | COMT (0.47) | MAPTKDM4ECDC7PLK4DYRK3 | |
| SCHEMBL24349225 | 0.78 | BPGM (0.57) | MAPTKDM4ECDC7PLK4DYRK3 | |
| SCHEMBL30445815 | 0.78 | BPGM (0.57) | MAPTKDM4ECDC7PLK4DYRK3 | |
| SCHEMBL24271914 | 0.77 | KDM4E (0.43) | MAPTKDM4ECDC7PLK4DYRK3 | |
| SCHEMBL30445389 | 0.77 | KDM4E (0.43) | MAPTKDM4ECDC7PLK4DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116406361-A | Compounds as modulators of phosphoglycerate mutase for the treatment of sickle cell disease | 健赞公司 | 2023-07-07 | — | — | CN | disclosed |