Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.56 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.55 |
| ▸ | CTSD | P07339 | 2/20 | 0.53 |
| ▸ | FNTA | P49354 | 3/20 | 0.52 |
| ▸ | FNTB | P49356 | 3/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30445027 | 0.93 | NAALAD2 (0.54) | BACE1BACE2NAALAD2CTSDMME | |
| SCHEMBL30331349 | 0.92 | OPRD1 (0.56) | BACE1BACE2CTSDFNTAFNTB | |
| SCHEMBL30445539 | 0.89 | MME (0.54) | FNTAFNTBMMENPY1RNPY2R | |
| SCHEMBL29735895 | 0.88 | NPY1R (0.53) | BACE1BACE2CTSDFNTAFNTB | |
| SCHEMBL30352879 | 0.88 | BACE1 (0.65) | BACE1BACE2CTSDNPY1RNPY2R | |
| SCHEMBL31278149 | 0.88 | ACE (0.53) | BACE1BACE2NAALAD2FNTAFNTB | |
| SCHEMBL30352847 | 0.88 | BACE1 (0.65) | BACE1BACE2CTSDNPY1RNPY2R | |
| SCHEMBL29523711 | 0.86 | BACE1 (0.56) | BACE1BACE2NAALAD2CTSDCASP1 | |
| SCHEMBL31319516 | 0.86 | BACE1 (0.59) | BACE1BACE2CTSD | |
| SCHEMBL30798078 | 0.86 | OPRD1 (0.59) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | claimed |
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | disclosed |