Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
| ▸ | CLK1 | P49759 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27779139 | 0.90 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL3319628 | 0.88 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL13973514 | 0.87 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL30858814 | 0.85 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL4861658 | 0.82 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL2639033 | 0.82 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL2639029 | 0.82 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL9186736 | 0.82 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL5460448 | 0.82 | HDAC6 (0.71) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL8402846 | 0.82 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230094176-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | CERENO SCIENT AB (SE) | 2023-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230094176-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC2, HDAC1 | MEN1 4196/4885KMT2A 215/4885ALDH1A1 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.