Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPGM | P07738 | 5/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24347962 | 1.00 | BPGM (0.80) | BPGMKDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL24348049 | 0.93 | BPGM (0.68) | BPGMKDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL24348025 | 0.89 | BPGM (0.74) | BPGMKDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL24348945 | 0.89 | BPGM (0.62) | BPGMKDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL24347958 | 0.89 | BPGM (1.00) | BPGMKDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL24349256 | 0.86 | BPGM (0.59) | BPGMKDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL24348487 | 0.85 | BPGM (0.57) | BPGMKDM4EMAPK1MAPTCDC7 | |
| SCHEMBL24349247 | 0.84 | BPGM (0.56) | BPGMKDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL24348018 | 0.82 | BPGM (0.87) | BPGMKDM4ERAB9AALDH1A1MAPK1 | |
| SCHEMBL24349242 | 0.81 | BPGM (0.73) | BPGMKDM4ERAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116406361-A | Compounds as modulators of phosphoglycerate mutase for the treatment of sickle cell disease | 健赞公司 | 2023-07-07 | — | — | CN | disclosed |