Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30123053 | 0.97 | ENPEP (0.53) | MMENPY1RNPY2RNPY4RNAALAD2 | |
| SCHEMBL31256994 | 0.94 | NPY1R (0.56) | MMENPY1RNPY2RNPY4RNAALAD2 | |
| SCHEMBL29630383 | 0.93 | NAALAD2 (0.56) | MMENPY1RNPY2RNPY4RNAALAD2 | |
| SCHEMBL29630449 | 0.92 | NAALAD2 (0.55) | NPY1RNPY2RNPY4RNAALAD2ENPEP | |
| SCHEMBL29596406 | 0.90 | MME (0.53) | MMEOPRM1 | |
| SCHEMBL29591937 | 0.90 | NAALAD2 (0.54) | NPY1RNPY2RNPY4RNAALAD2ENPEP | |
| SCHEMBL29630754 | 0.90 | NAALAD2 (0.54) | NPY1RNPY2RNPY4RNAALAD2ENPEP | |
| SCHEMBL29630373 | 0.89 | NPY1R (0.52) | NPY1RNPY2RNPY4RNAALAD2ENPEP | |
| SCHEMBL29608986 | 0.89 | NPY4R (0.57) | MMENPY1RNPY2RNPY4RNAALAD2 | |
| SCHEMBL38651006 | 0.88 | NAALAD2 (0.57) | NPY1RNPY2RNPY4RNAALAD2ENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | claimed |
| EP-4192843-A1 | PEPTIDES ABLE TO BIND ANGIOTENSIN-CONVERTING ENZYME 2 (ACE2) AND MEDICAL USES THEREOF | Ospedale Pediatrico Bambino Gesù (IT) | 2023-06-14 | — | — | EP | disclosed |