Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448757 | 0.83 | MAPT (0.57) | GAAMEN1KMT2AMAPTPOLB | |
| SCHEMBL16956544 | 0.77 | CYP2C9 (0.55) | GAAMEN1KMT2AMAPTPOLB | |
| SCHEMBL30446001 | 0.77 | SMN1; SMN2 (0.57) | KMT2AMAPTSMN1; SMN2CYP3A4TSHR | |
| SCHEMBL547153 | 0.75 | CYP1A2 (0.63) | GAAMEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL30307376 | 0.75 | CYP1A2 (0.63) | GAAMEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL29467205 | 0.74 | MAPT (0.64) | GAAMEN1KMT2AMAPTPOLB | |
| SCHEMBL30506314 | 0.74 | RECQL (0.77) | GAAMEN1KMT2AMAPTPOLB | |
| SCHEMBL4221613 | 0.74 | RECQL (0.77) | GAAMEN1KMT2AMAPTPOLB | |
| SCHEMBL4864755 | 0.74 | MAPT (0.64) | GAAMEN1KMT2AMAPTPOLB | |
| SCHEMBL1660322 | 0.74 | RECQL (0.77) | GAAMEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143718-B | Anti-hepatitis B activity (E) - (3-phenyl isoxazole-5-) -methylene acetophenone oxime ether derivatives | 广西大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-116143718-A | Anti-hepatitis B activity (E) - (3-phenyl isoxazole-5-) -methylene acetophenone oxime ether derivatives | 广西大学 | 2023-05-23 | — | — | CN | disclosed |