Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | FAAH | O00519 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | PTGES | O14684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25234022 | 1.00 | GAA (0.77) | GAASMN1; SMN2KDM4EFAAHHSD17B10 | |
| SCHEMBL2739989 | 0.87 | SMN1; SMN2 (1.00) | GAASMN1; SMN2KDM4EFAAHHSD17B10 | |
| SCHEMBL2739987 | 0.86 | KDM4E (0.80) | GAASMN1; SMN2KDM4EFAAHHSD17B10 | |
| SCHEMBL9926443 | 0.83 | SMN1; SMN2 (0.82) | GAASMN1; SMN2KDM4EHSD17B10SIRT1 | |
| SCHEMBL2739979 | 0.82 | SMN1; SMN2 (0.77) | GAASMN1; SMN2KDM4EFAAHHSD17B10 | |
| SCHEMBL9926412 | 0.81 | SMN1; SMN2 (0.82) | GAASMN1; SMN2KDM4EHSD17B10SIRT1 | |
| SCHEMBL22504409 | 0.81 | HSD17B10 (1.00) | GAASMN1; SMN2KDM4EFAAHHSD17B10 | |
| SCHEMBL2739978 | 0.80 | SIRT1 (0.84) | GAASMN1; SMN2KDM4EHSD17B10SIRT1 | |
| SCHEMBL5309636 | 0.79 | SIRT1 (0.78) | GAASMN1; SMN2KDM4EHSD17B10SIRT1 | |
| SCHEMBL16384038 | 0.79 | KDM4E (1.00) | GAASMN1; SMN2KDM4EHSD17B10SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172913-A1 | COMPOUNDS FOR USE IN THE REACTIVATION OF HIV IN LATENT HIV-INFECTED CELLS | TARBP1, NFATC1, TARDBP | GAA 1157/4885SMN1; SMN2 4842/4885KDM4E 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.