SCHEMBL30445913

SCHEMBL30445913

COC(=O)c1ccc2c(c1)CCN2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
KDM4E B2RXH2 2/20 0.54
ALDH1A1 P00352 4/20 0.50
ALOX15 P16050 2/20 0.50
DRD2 P14416 1/20 0.50
DRD4 P21917 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
CRBN Q96SW2 2/20 0.49
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
XDH P47989 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ACHE P22303 3/20 0.44
GAA P10253 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288320 1.00 MAPT (0.54) MAPTKDM4EALDH1A1ALOX15DRD2
Hydrochloric Acid SCHEMBL699425 0.98 MAPT (0.53) MAPTKDM4EALDH1A1ALOX15DRD2
SCHEMBL29995197 0.91 MAPT (0.68) MAPTKDM4EALDH1A1ALOX15CYP2C9
SCHEMBL45146 0.91 MAPT (0.68) MAPTKDM4EALDH1A1ALOX15CYP2C9
Hydrochloric Acid SCHEMBL1856980 0.89 MAPT (0.66) MAPTKDM4EALDH1A1ALOX15CYP2C9
SCHEMBL23063918 0.88 CRBN (0.48) MAPTKDM4EALDH1A1ALOX15DRD2
Hydrochloric Acid SCHEMBL1264485 0.88 MAPT (0.60) MAPTKDM4EALDH1A1ALOX15CYP2C9
SCHEMBL2898350 0.87 ALDH1A1 (0.47) MAPTKDM4EALDH1A1ALOX15CRBN
SCHEMBL29906783 0.87 ALDH1A1 (0.47) MAPTKDM4EALDH1A1ALOX15CRBN
Hydrochloric Acid SCHEMBL29940234 0.86 ALDH1A1 (0.46) MAPTKDM4EALDH1A1ALOX15CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116145156-B Indoline compound preparation method based on organic electronic synthesis 六盘水师范学院 2026-05-15 CN disclosed
CN-116145156-A Indoline compound preparation method based on organic electronic synthesis 六盘水师范学院 2023-05-23 CN disclosed