SCHEMBL30446531

SCHEMBL30446531

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CS)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NTSR2 O95665 13/20 0.55
▸ NTSR1 P30989 12/20 0.55
▸ SORT1 Q99523 11/20 0.55
▸ SLC6A2 P23975 1/20 0.54
▸ REN P00797 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30249075 0.96 NTSR2 (0.57) NTSR2NTSR1SORT1SLC6A2REN
SCHEMBL30446673 0.94 NTSR2 (0.56) NTSR2NTSR1SORT1SLC6A2REN
SCHEMBL30249014 0.93 SLC6A2 (0.62) NTSR2NTSR1SORT1SLC6A2REN
SCHEMBL30249030 0.93 NTSR2 (0.58) NTSR2NTSR1SORT1SLC6A2REN
SCHEMBL30249139 0.93 NTSR2 (0.61) NTSR2NTSR1SORT1SLC6A2REN
SCHEMBL30446679 0.91 NTSR2 (0.55) NTSR2NTSR1SORT1SLC6A2REN
SCHEMBL29737387 0.90 SLC6A2 (0.62) NTSR2NTSR1SORT1SLC6A2REN
SCHEMBL30248936 0.89 SLC6A2 (0.53) NTSR2NTSR1SORT1SLC6A2
SCHEMBL30446614 0.89 NTSR2 (0.56) NTSR2NTSR1SORT1SLC6A2REN
SCHEMBL30248974 0.88 SLC6A2 (0.66) NTSR2NTSR1SORT1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174582-A1 VIPR2 ANTAGONIST PEPTIDE ICHIMARU PHARCOS CO., LTD. (JP) 2023-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174582-A1 VIPR2 ANTAGONIST PEPTIDE VIPR2, NPY2R, NPY5R NTSR2 64/4885NTSR1 170/4885SORT1 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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