SCHEMBL30249014

SCHEMBL30249014

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 1/20 0.62
▸ NTSR2 O95665 8/20 0.55
▸ NTSR1 P30989 8/20 0.55
▸ SORT1 Q99523 7/20 0.55
▸ OPRM1 P35372 2/20 0.55
▸ OPRD1 P41143 1/20 0.55
▸ NMUR2 Q9GZQ4 1/20 0.54
▸ NMUR1 Q9HB89 1/20 0.54
▸ REN P00797 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30248974 0.95 SLC6A2 (0.66) SLC6A2NTSR2NTSR1SORT1OPRM1
SCHEMBL30249030 0.94 NTSR2 (0.58) SLC6A2NTSR2NTSR1SORT1REN
SCHEMBL30446531 0.93 NTSR2 (0.55) SLC6A2NTSR2NTSR1SORT1REN
SCHEMBL30248936 0.92 SLC6A2 (0.53) SLC6A2NTSR2NTSR1SORT1NMUR2
SCHEMBL30249009 0.92 SLC6A2 (0.63) SLC6A2NTSR2NTSR1SORT1OPRM1
SCHEMBL30248935 0.89 REN (0.52) SLC6A2NTSR2NTSR1SORT1NMUR2
SCHEMBL30249075 0.89 NTSR2 (0.57) SLC6A2NTSR2NTSR1SORT1REN
SCHEMBL31362642 0.89 SLC6A2 (0.75) SLC6A2OPRM1OPRD1NMUR2NMUR1
SCHEMBL30446614 0.88 NTSR2 (0.56) SLC6A2NTSR2NTSR1SORT1NMUR2
SCHEMBL30478148 0.88 SLC6A2 (0.59) SLC6A2NTSR2NTSR1SORT1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174582-A1 VIPR2 ANTAGONIST PEPTIDE ICHIMARU PHARCOS CO., LTD. (JP) 2023-06-08 — — US disclosed
EP-4137502-A1 VIPR2 ANTAGONIST PEPTIDE Ichimaru Pharcos Co., Ltd. (JP) 2023-02-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174582-A1 VIPR2 ANTAGONIST PEPTIDE VIPR2, NPY2R, NPY5R SLC6A2 1059/4885NTSR2 64/4885NTSR1 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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