Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21116397 | 1.00 | ATF4 (0.56) | ATF4 | |
| SCHEMBL21116463 | 0.87 | ATF4 (0.61) | ATF4 | |
| SCHEMBL21117011 | 0.87 | ATF4 (0.56) | ATF4 | |
| SCHEMBL21116392 | 0.86 | ATF4 (0.50) | ATF4 | |
| SCHEMBL22661766 | 0.85 | ATF4 (0.54) | ATF4 | |
| SCHEMBL19577472 | 0.85 | ATF4 (0.59) | ATF4 | |
| SCHEMBL19577123 | 0.85 | ATF4 (0.59) | ATF4 | |
| SCHEMBL19577448 | 0.85 | ATF4 (0.59) | ATF4 | |
| SCHEMBL19577344 | 0.85 | ATF4 (0.59) | ATF4 | |
| SCHEMBL30682442 | 0.85 | ATF4 (0.59) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704089-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2023-07-19 | — | — | EP | disclosed |