⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10539773 | 1.00 | — | — | |
| SCHEMBL6894066 | 0.82 | HCAR2 (0.36) | — | |
| SCHEMBL187616 | 0.80 | — | — | |
| SCHEMBL28404629 | 0.80 | ALDH1A1 (0.60) | — | |
| SCHEMBL12315103 | 0.80 | ALDH1A1 (0.60) | — | |
| SCHEMBL306274 | 0.79 | TSHR (0.43) | — | |
| SCHEMBL26441580 | 0.79 | ALDH1A1 (0.52) | — | |
| SCHEMBL3815702 | 0.79 | TSHR (0.38) | — | |
| SCHEMBL10663016 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL10662875 | 0.79 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746394-B | Aryl propionic acid derivative, pharmaceutical composition, and preparation method and application thereof | 南京海融医药科技股份有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-114478391-B | Ornidazole ester prodrug, pharmaceutical composition, and preparation method and application thereof | 南京锐志生物医药有限公司 | 2023-09-15 | — | — | CN | claimed |
| US-7153972-B2 | Benzimidazole derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2006-12-26 | — | — | US | claimed |
| US-20050131039-A1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. | 2005-06-16 | — | — | US | claimed |
| US-20040044223-A1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. | 2004-03-04 | — | — | US | claimed |
| US-20020151723-A1 | Benzimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. | 2002-10-17 | — | — | US | claimed |
| US-4935508-A | Acylation of 7-aminocephalosporin with alkyl 2-(2-amino-thiazol-4-yl)-2-oximinoacetate | BRISTOL-MYERS COMPANY (US) | 1990-06-19 | — | — | US | claimed |
| JP-60084292-A | — | — | None | — | — | JP | disclosed |
| CN-114728883-B | Ibuprofen ester prodrug, pharmaceutical composition, preparation method and application | 南京海融医药科技股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115836047-B | Aryl propionic acid derivative and emulsion preparation thereof | 南京海融医药科技股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-114746394-B | Aryl propionic acid derivative, pharmaceutical composition, and preparation method and application thereof | 南京海融医药科技股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116675650-B | Lithium ion battery electrolyte additive, lithium ion battery electrolyte and lithium ion battery | 蓝固(淄博)新能源科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-114478391-B | Ornidazole ester prodrug, pharmaceutical composition, and preparation method and application thereof | 南京锐志生物医药有限公司 | 2023-09-15 | — | — | CN | disclosed |
| US-4464299-A | Antibacterial carbapenem compounds | SHIONOGI & CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0108942-A2 | Cephalosporin derivatives, methods of production thereof and prophylactic and therapeutic agents for bacterial infection | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1984-05-23 | — | — | EP | disclosed |
| EP-0105919-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES. | CIBA GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |
| WO-1983003828-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-11-10 | — | — | WO | disclosed |
| EP-0061162-A2 | Cephalosporin derivatives, pharmaceutical compositions containing the same and production thereof | KYOTO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1982-09-29 | — | — | EP | disclosed |
| EP-0049118-A2 | Cephalosporin derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-04-07 | — | — | EP | disclosed |
| US-4264595-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-04-28 | — | — | US | disclosed |