SCHEMBL30449477

SCHEMBL30449477

Cc1cc(=O)n(C)c2c(O)c(F)ccc12

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 9/20 0.51
CYP19A1 P11511 9/20 0.51
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.41
KAT2B Q92831 1/20 0.38
HIF1A Q16665 4/20 0.36
BRD9 Q9H8M2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
CASP6 P55212 1/20 0.34
PAX8 Q06710 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22490611 1.00 NQO2 (0.51) NQO2CYP19A1KDM4EMAPTKAT2B
SCHEMBL4328945 0.81 NQO2 (0.51) NQO2CYP19A1KDM4EMAPTKAT2B
SCHEMBL21820274 0.81 NQO2 (0.51) NQO2CYP19A1KDM4EKAT2BBRD9
SCHEMBL21820270 0.75 NQO2 (0.46) NQO2CYP19A1KDM4EMAPTKAT2B
SCHEMBL29712035 0.75 NQO2 (0.46) NQO2CYP19A1KDM4EMAPTKAT2B
SCHEMBL21820236 0.74 NQO2 (0.45) NQO2CYP19A1KDM4EKAT2BBRD9
SCHEMBL12998227 0.74 NQO2 (0.51) NQO2CYP19A1KDM4EMAPTKAT2B
SCHEMBL4330683 0.73 NQO2 (0.45) NQO2CYP19A1KDM4EMAPTKAT2B
SCHEMBL11217793 0.73 MAPT (0.67) NQO2CYP19A1KDM4EMAPTALDH1A1
SCHEMBL30448891 0.73 BRPF1 (0.40) MAPTKAT2BHIF1ABRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111527093-B Antibacterial heterocyclic compounds and synthesis thereof 巴格沃克斯研究有限公司 2023-06-09 CN disclosed