Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | RHOC | P08134 | 1/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22797803 | 1.00 | SCN9A (0.68) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22809520 | 0.94 | SCN9A (0.62) | SCN9AKDM4EKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL22798285 | 0.93 | SCN9A (0.66) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL20595207 | 0.92 | SCN9A (0.65) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL30450908 | 0.92 | SCN9A (0.65) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22797788 | 0.92 | SCN9A (0.75) | SCN9AMRGPRX4SMN1; SMN2 | |
| SCHEMBL22797766 | 0.90 | SCN9A (0.73) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22798289 | 0.90 | SCN9A (0.54) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22798435 | 0.88 | SCN9A (0.53) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL30449642 | 0.88 | SCN9A (0.53) | SCN9AALDH1A1KDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | claimed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |