Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798435 | 1.00 | SCN9A (0.53) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22798288 | 0.93 | SCN9A (0.51) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22798228 | 0.92 | SCN9A (0.51) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22798328 | 0.92 | SCN9A (0.59) | SCN9AMRGPRX4RHOCRHOA | |
| SCHEMBL22798289 | 0.90 | SCN9A (0.54) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22797781 | 0.90 | SCN9A (0.57) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22797756 | 0.89 | SCN9A (0.51) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22797803 | 0.88 | SCN9A (0.68) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL30449593 | 0.88 | SCN9A (0.68) | SCN9AALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL22797748 | 0.88 | SCN9A (0.56) | SCN9APPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | claimed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |