SCHEMBL3044966

SCHEMBL3044966

O=C(CCCl)Nc1ccc(-c2nc(CC(Cl)(Cl)Cl)nc(CC(Cl)(Cl)Cl)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.44
MAPT P10636 6/20 0.40
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 4/20 0.40
HPGD P15428 4/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
SMN1; SMN2 Q16637 5/20 0.39
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
MITF O75030 1/20 0.39
HTT P42858 1/20 0.39
ADORA3 P0DMS8 4/20 0.38
RXFP1 Q9HBX9 1/20 0.38
CASP3 P42574 3/20 0.37
SENP8 Q96LD8 2/20 0.37
SENP7 Q9BQF6 2/20 0.37
SENP6 Q9GZR1 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CASP2 P42575 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL393443 0.81 TP53 (0.46) TP53MAPTALDH1A1KDM4EHPGD
SCHEMBL4683731 0.72 CYP1A2 (0.56) TP53MAPTALDH1A1HPGDCYP1A2
SCHEMBL11417562 0.70 MAPT (0.55) TP53MAPTALDH1A1HPGDMEN1
SCHEMBL9486121 0.69 TP53 (0.50) TP53MAPTALDH1A1HPGDMEN1
SCHEMBL1325326 0.68 ALDH1A1 (0.66) TP53MAPTALDH1A1HPGDMEN1
SCHEMBL2205077 0.68 CYP1A1 (0.67) TP53MAPTALDH1A1HPGDMEN1
SCHEMBL3317660 0.67 HDAC3 (0.62) TP53MAPTALDH1A1KDM4EMEN1
SCHEMBL11720766 0.67 KMT2A (0.68) TP53HPGDMEN1KMT2ASMN1; SMN2
SCHEMBL28778390 0.67 POLB (0.68) TP53MAPTALDH1A1MEN1KMT2A
SCHEMBL6621438 0.66 POLB (0.56) TP53MAPTALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7645545-B2 Colorant-containing curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20060246364-A1 Colorant-containing curable composition, color filter and production method thereof FUJI PHOTO FILM CO., LTD. 2006-11-02 US disclosed