Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.56 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22797748 | 1.00 | SCN9A (0.56) | SCN9ASCN10APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL30449642 | 0.88 | SCN9A (0.53) | SCN9APPARD | |
| SCHEMBL22798435 | 0.88 | SCN9A (0.53) | SCN9APPARD | |
| SCHEMBL20595163 | 0.88 | SCN9A (0.49) | SCN9ASCN10ASCN7AKCNH2SCN5A | |
| SCHEMBL22798288 | 0.86 | SCN9A (0.51) | SCN9APPARD | |
| SCHEMBL22798328 | 0.85 | SCN9A (0.59) | SCN9A | |
| SCHEMBL22798228 | 0.85 | SCN9A (0.51) | SCN9A | |
| SCHEMBL22797781 | 0.85 | SCN9A (0.57) | SCN9APPARD | |
| SCHEMBL20595155 | 0.84 | SCN9A (0.65) | SCN9ASCN10APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL22798237 | 0.84 | SCN9A (0.79) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | claimed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |