Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | RHOC | P08134 | 3/20 | 0.38 |
| ▸ | RHOA | P61586 | 3/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798309 | 1.00 | SCN9A (0.59) | SCN9AMAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20595230 | 0.86 | SCN9A (0.58) | SCN9AMAPTCYP3A4KMT2AALDH1A1 | |
| SCHEMBL20595204 | 0.86 | SCN9A (0.78) | SCN9AMAPTKMT2AALDH1A1PPARD | |
| SCHEMBL30449788 | 0.86 | SCN9A (0.58) | SCN9AMAPTCYP3A4KMT2AALDH1A1 | |
| SCHEMBL30449602 | 0.86 | SCN9A (0.78) | SCN9AMAPTKMT2AALDH1A1PPARD | |
| SCHEMBL22798301 | 0.84 | SCN9A (0.59) | SCN9AMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL30449765 | 0.84 | SCN9A (0.59) | SCN9AMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL22798304 | 0.83 | SCN9A (0.82) | SCN9AKMT2AALDH1A1MEN1PPARD | |
| SCHEMBL30450216 | 0.83 | SCN9A (0.82) | SCN9AKMT2AALDH1A1MEN1PPARD | |
| SCHEMBL22798281 | 0.83 | SCN9A (0.58) | SCN9AMAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | claimed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |