Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.78 |
| ▸ | RHOC | P08134 | 1/20 | 0.44 |
| ▸ | RHOA | P61586 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595204 | 1.00 | SCN9A (0.78) | SCN9ARHOCRHOAALDH1A1SMN1; SMN2 | |
| SCHEMBL22798304 | 0.97 | SCN9A (0.82) | SCN9ARHOCRHOAALDH1A1SMN1; SMN2 | |
| SCHEMBL30450216 | 0.97 | SCN9A (0.82) | SCN9ARHOCRHOAALDH1A1SMN1; SMN2 | |
| SCHEMBL22798237 | 0.88 | SCN9A (0.79) | SCN9ARHOCRHOAALDH1A1SMN1; SMN2 | |
| SCHEMBL22809571 | 0.88 | SCN9A (0.61) | SCN9ARHOCRHOASMN1; SMN2KMT2A | |
| SCHEMBL22798213 | 0.88 | SCN9A (1.00) | SCN9ARHOCRHOAALDH1A1SMN1; SMN2 | |
| SCHEMBL22797771 | 0.87 | SCN9A (0.77) | SCN9ARHOCRHOAALDH1A1SMN1; SMN2 | |
| SCHEMBL22798309 | 0.86 | SCN9A (0.59) | SCN9ARHOCRHOAALDH1A1KMT2A | |
| SCHEMBL20595173 | 0.86 | SCN9A (0.77) | SCN9ARHOCRHOAALDH1A1SMN1; SMN2 | |
| SCHEMBL30449741 | 0.86 | SCN9A (0.59) | SCN9ARHOCRHOAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | claimed |
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |