Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30450029 | 1.00 | LMNA (0.45) | LMNASCN9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL28350965 | 1.00 | LMNA (0.45) | LMNASCN9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL20595187 | 0.86 | SCN9A (0.50) | LMNASCN9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL20595194 | 0.86 | SCN9A (0.50) | LMNASCN9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL20595185 | 0.86 | SCN9A (0.50) | LMNASCN9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL28999002 | 0.81 | SMN1; SMN2 (0.49) | LMNASCN9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL28999003 | 0.81 | SMN1; SMN2 (0.49) | LMNASCN9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL28999190 | 0.78 | MAPK1 (0.47) | LMNASCN9ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL783971 | 0.78 | MAPK1 (0.53) | LMNASMN1; SMN2MAPK1ALDH1A1KMT2A | |
| SCHEMBL28350962 | 0.78 | MAPK1 (0.47) | LMNASCN9ASMN1; SMN2MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |