Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.41 |
| ▸ | CLK2 | P49760 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL20595199 | 1.00 | GSK3A (0.41) | GSK3AGSK3BCLK4KDRPRKD3 | |
| SCHEMBL22809487 | 0.91 | GAK (0.45) | GSK3AGSK3BCLK4KDRPRKD3 | |
| Trifluoroacetic Acid SCHEMBL30450237 | 0.88 | PTGDR2 (0.36) | GSK3AGSK3BCLK4KDRPRKD3 | |
| SCHEMBL20595203 | 0.83 | CLK4 (0.43) | GSK3AGSK3BCLK4KDRPRKD3 | |
| SCHEMBL28351290 | 0.82 | CLK4 (0.42) | GSK3AGSK3BCLK4KDRPRKD3 | |
| SCHEMBL28666661 | 0.81 | PTGDR2 (0.53) | GSK3AGSK3BCLK4KDRPRKD3 | |
| SCHEMBL4419956 | 0.78 | GAK (0.45) | GSK3AGSK3BCLK4KDRPRKD3 | |
| SCHEMBL15473239 | 0.78 | GAK (0.48) | GSK3AGSK3BCLK4KDRPRKD3 | |
| SCHEMBL12968479 | 0.77 | GAK (0.47) | GSK3AGSK3BCLK4KDRPRKD3 | |
| SCHEMBL29878377 | 0.77 | ALDH1A1 (0.54) | GSK3AGSK3BCLK4KDRPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612285-B | Amide derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2023-04-04 | — | — | CN | disclosed |