Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25305115 | 0.88 | LCK (0.51) | LCKPIK3CGP2RX3KMT2APDPK1 | |
| SCHEMBL31114539 | 0.88 | LCK (0.52) | LCKP2RX3KMT2APDPK1DYRK1A | |
| SCHEMBL25303173 | 0.88 | LCK (0.52) | LCKP2RX3KMT2APDPK1DYRK1A | |
| SCHEMBL30450911 | 0.83 | LCK (0.46) | LCKPIK3CADYRK1AEPHX2 | |
| SCHEMBL30451627 | 0.82 | LCK (0.49) | LCKPIK3CGKMT2AEPHX2 | |
| SCHEMBL30451439 | 0.81 | LCK (0.46) | LCKP2RX3KMT2APIK3CAPDPK1 | |
| SCHEMBL30450350 | 0.79 | LCK (0.51) | LCKKMT2APDPK1DYRK1AEPHX2 | |
| SCHEMBL25259089 | 0.78 | PIK3CD (0.50) | LCKDYRK1A | |
| SCHEMBL31114491 | 0.78 | PIK3CD (0.50) | LCKDYRK1A | |
| SCHEMBL25260578 | 0.77 | LCK (0.50) | LCKDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4460500-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |