Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 11/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.39 |
| ▸ | CCNK | O75909 | 6/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 6/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.38 |
| ▸ | CDK9 | P50750 | 5/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 4/20 | 0.36 |
| ▸ | CCNH | P51946 | 4/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 4/20 | 0.36 |
| ▸ | CDK1 | P06493 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.36 |
| ▸ | CCND1 | P24385 | 3/20 | 0.36 |
| ▸ | CCND3 | P30281 | 3/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | WNT3 | P56703 | 2/20 | 0.34 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22977511 | 0.84 | IDH1 (0.48) | CDK2CCNE1CCNT1CDK9ALK | |
| SCHEMBL30449867 | 0.82 | ALK (0.41) | ALKTRPV1WNT3SFRP1 | |
| SCHEMBL22997632 | 0.81 | CDK4 (0.43) | CDK2CCNE1CCNKCDK12CCNT1 | |
| SCHEMBL22997627 | 0.81 | CDK4 (0.43) | CDK2CCNE1CCNKCDK12CCNT1 | |
| SCHEMBL22983953 | 0.74 | CCNE1 (0.50) | CDK2CCNE1CCNKCDK12CCNT1 | |
| SCHEMBL22977388 | 0.74 | CCNE1 (0.40) | CDK2CCNE1CCNKCDK12CCNT1 | |
| SCHEMBL30449440 | 0.74 | ALK (0.41) | CDK2CCNKCDK9ALKCDK4 | |
| SCHEMBL22977357 | 0.72 | CCNE1 (0.72) | CDK2CCNE1CCNT1CDK9CDK7 | |
| SCHEMBL29820627 | 0.72 | CCNE1 (0.72) | CDK2CCNE1CCNT1CDK9CDK7 | |
| SCHEMBL29091778 | 0.71 | GPR119 (0.46) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348458-A | Imidazolylpyrimidinylamine compounds as CDK2 inhibitors | 因赛特公司 | 2023-06-27 | — | — | CN | disclosed |