Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23985887 | 1.00 | ALDH1A1 (0.60) | ALDH1A1TSHRNPSR1MAOBTAS1R3 | |
| SCHEMBL23985268 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TSHRNPSR1MAOBTAS1R3 | |
| SCHEMBL30305464 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TSHRNPSR1MAOBTAS1R3 | |
| SCHEMBL23985881 | 0.83 | MAPT (0.58) | ALDH1A1HTTHPGDLMNARXFP1 | |
| SCHEMBL23156377 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHRNPSR1MAOBTAS1R3 | |
| SCHEMBL25192848 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TSHRNPSR1MAOBTAS1R3 | |
| SCHEMBL26690149 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TSHRNPSR1MAOBTAS1R3 | |
| SCHEMBL29766092 | 0.76 | TSHR (0.54) | ALDH1A1TSHRNPSR1MAOBTAS1R3 | |
| SCHEMBL23115900 | 0.76 | TSHR (0.54) | ALDH1A1TSHRNPSR1MAOBTAS1R3 | |
| SCHEMBL4927411 | 0.76 | MEN1 (0.77) | ALDH1A1TSHRNPSR1MAOBTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |