Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313840 | 1.00 | NFKB1 (0.64) | NFKB1CA1CA2CA4LMNA | |
| SCHEMBL2313844 | 1.00 | NFKB1 (0.64) | NFKB1CA1CA2CA4LMNA | |
| SCHEMBL69543 | 0.91 | NFKB1 (0.75) | NFKB1CA1CA2CA4LMNA | |
| SCHEMBL459291 | 0.91 | NFKB1 (0.75) | NFKB1CA1CA2CA4LMNA | |
| SCHEMBL31197561 | 0.91 | NFKB1 (0.75) | NFKB1CA1CA2CA4LMNA | |
| Bromide SCHEMBL8376004 | 0.89 | NFKB1 (0.72) | NFKB1CA1CA2CA4LMNA | |
| Hydrochloric Acid SCHEMBL8374050 | 0.89 | NFKB1 (0.72) | NFKB1CA1CA2CA4LMNA | |
| SCHEMBL11121643 | 0.83 | HCAR2 (0.75) | NFKB1CA1CA2CA4LMNA | |
| SCHEMBL9072389 | 0.82 | NFKB1 (0.53) | NFKB1CA1CA2CA4LMNA | |
| SCHEMBL31549898 | 0.82 | MAPT (0.60) | NFKB1LMNAMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109928949-B | Preparation of fluorescent probe and application of long-term stable imaging lysosome thereof | 兰州大学 | 2023-05-26 | — | — | CN | disclosed |