Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26712506 | 1.00 | CA1 (0.67) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL14348204 | 0.84 | CA1 (0.73) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL30305417 | 0.82 | PARK7 (0.54) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL5779243 | 0.81 | CA1 (0.69) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL16863040 | 0.81 | CA1 (0.68) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL23985223 | 0.81 | KDM4E (0.76) | KDM4ECASP3L3MBTL1ALDH1A1MAPT | |
| SCHEMBL31667598 | 0.81 | KDM4E (0.67) | KDM4ECASP3L3MBTL1ALDH1A1MAPT | |
| SCHEMBL18669037 | 0.81 | CA9 (0.67) | CA1CA2CA9CA12KDM4E | |
| SCHEMBL20877391 | 0.80 | KDM4E (0.65) | KDM4ECASP3L3MBTL1ALDH1A1MAPT | |
| SCHEMBL30428778 | 0.80 | KDM4E (0.65) | KDM4ECASP3L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |