Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252346 | 1.00 | PDE10A (0.37) | PDE10AGABRA1GABRB2KITDHFR | |
| SCHEMBL26771191 | 0.92 | PDE10A (0.36) | PDE10AGABRA1GABRB2KITDHFR | |
| SCHEMBL31753947 | 0.88 | PDE10A (0.36) | PDE10AGABRA1GABRB2KITDHFR | |
| SCHEMBL24252274 | 0.88 | PDE10A (0.36) | PDE10AGABRA1GABRB2KITDHFR | |
| SCHEMBL24252973 | 0.86 | — | — | |
| SCHEMBL24252260 | 0.82 | PDE10A (0.46) | PDE10ADHFR | |
| SCHEMBL30467809 | 0.82 | PDE10A (0.46) | PDE10ADHFR | |
| SCHEMBL30451479 | 0.81 | PDE10A (0.42) | PDE10A | |
| SCHEMBL24252629 | 0.81 | PDE10A (0.42) | PDE10A | |
| SCHEMBL26771132 | 0.81 | PDE10A (0.35) | PDE10AGABRA1GABRB2KITDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |