Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578812 | 1.00 | KDM4E (0.71) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| Formic Acid SCHEMBL30451955 | 0.88 | KDM4E (0.56) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL221530 | 0.84 | KDM4E (1.00) | KDM4ESMN1; SMN2ALDH1A1RAB9AKMT2A | |
| SCHEMBL31416835 | 0.84 | KDM4E (1.00) | KDM4ESMN1; SMN2ALDH1A1RAB9AKMT2A | |
| SCHEMBL89446 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1NPC1RAB9AESR1 | |
| Trifluoroacetic Acid SCHEMBL29015449 | 0.82 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1ESR1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27658861 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9AESR1 | |
| Chlorobenzene SCHEMBL27858714 | 0.80 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL20116540 | 0.76 | KDM4E (0.39) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL30502565 | 0.74 | KDM4E (0.43) | KDM4ECYP1A2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715231-A | Complement factor inhibitors and uses thereof | 安尼艾克松股份有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |