Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | C1S | P09871 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451373 | 0.82 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL2578812 | 0.82 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1CYP1A2HPGD | |
| Formic Acid SCHEMBL30451955 | 0.80 | KDM4E (0.56) | KDM4EHSD17B10TP53TDP1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29015415 | 0.73 | C1S (0.62) | KDM4EC1STP53TDP1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL30452000 | 0.72 | C1S (0.43) | KDM4EC1SHSD17B10TP53ALDH1A1 | |
| SCHEMBL89446 | 0.70 | SMN1; SMN2 (0.58) | ALDH1A1CYP1A2L3MBTL1RXFP1ESR1 | |
| SCHEMBL31416835 | 0.70 | KDM4E (1.00) | KDM4EHSD17B10TP53TDP1ALDH1A1 | |
| SCHEMBL221530 | 0.70 | KDM4E (1.00) | KDM4EHSD17B10TP53TDP1ALDH1A1 | |
| Aminacrine SCHEMBL29566950 | 0.69 | ALDH1A1 (0.67) | KDM4EHSD17B10TP53TDP1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL18096685 | 0.69 | KDM4E (0.67) | KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |