Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 3/20 | 0.38 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26732593 | 1.00 | MAPT (0.45) | MAPTPARP1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL29426569 | 0.87 | MAPT (0.44) | MAPTPARP1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL24076896 | 0.87 | MAPT (0.44) | MAPTPARP1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL29426515 | 0.81 | PARP1 (0.42) | MAPTPARP1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL26732910 | 0.81 | PARP1 (0.42) | MAPTPARP1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL26732624 | 0.78 | PRMT5 (0.43) | PRMT5WDR77AURKBROCK1 | |
| SCHEMBL24076862 | 0.78 | MAPT (0.47) | MAPTPARP1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL24076281 | 0.75 | POLB (0.40) | MAPTSMN1; SMN2PRMT5WDR77PDE2A | |
| SCHEMBL24076899 | 0.75 | MAPT (0.53) | MAPTPARP1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL31014304 | 0.75 | ATM (0.61) | MAPTSMN1; SMN2PRMT5AURKBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261456-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2023-06-13 | — | — | CN | disclosed |