Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 10/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032717 | 1.00 | ABL1 (0.51) | ABL1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29032795 | 0.91 | ABL1 (0.55) | ABL1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30452209 | 0.91 | ABL1 (0.55) | ABL1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29032721 | 0.91 | NPC1 (0.52) | ABL1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30450725 | 0.91 | NPC1 (0.52) | ABL1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29032700 | 0.90 | ABL1 (0.52) | ABL1HTTMMP2MMP9MMP8 | |
| SCHEMBL30450655 | 0.88 | ABL1 (0.53) | ABL1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29032771 | 0.88 | ABL1 (0.53) | ABL1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29032732 | 0.87 | NPC1 (0.49) | ABL1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29032706 | 0.86 | P2RY14 (0.51) | ABL1HTTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | claimed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | claimed |
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |