Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29032795 | 1.00 | ABL1 (0.55) | ABL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL29032771 | 0.93 | ABL1 (0.53) | ABL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL30450655 | 0.93 | ABL1 (0.53) | ABL1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL30451563 | 0.91 | ABL1 (0.51) | ABL1NPC1RAB9ASMN1; SMN2MMP2 | |
| SCHEMBL29032717 | 0.91 | ABL1 (0.51) | ABL1NPC1RAB9ASMN1; SMN2MMP2 | |
| SCHEMBL29032706 | 0.91 | P2RY14 (0.51) | ABL1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL29032700 | 0.90 | ABL1 (0.52) | ABL1MMP2MMP9MMP8HTT | |
| SCHEMBL29032732 | 0.86 | NPC1 (0.49) | ABL1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL29032780 | 0.84 | HTT (0.53) | ABL1NPC1RAB9ASMN1; SMN2MMP2 | |
| SCHEMBL30451514 | 0.84 | ABL1 (0.56) | ABL1NPC1RAB9ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253686-B | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-17 | — | — | CN | disclosed |
| CN-116253686-A | Aminobenzimidazole benzamide derivative and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-13 | — | — | CN | disclosed |