Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26732579 | 1.00 | ALOX15 (0.38) | ALOX15PIM1PLAUPDPK1JAK2 | |
| SCHEMBL29426530 | 0.91 | ALOX15 (0.38) | ALOX15PIM1PLAUPDPK1JAK2 | |
| SCHEMBL26732576 | 0.91 | ALOX15 (0.38) | ALOX15PIM1PLAUPDPK1JAK2 | |
| SCHEMBL2462679 | 0.89 | ALOX15 (0.42) | ALOX15PIM1PLAUPDPK1JAK2 | |
| SCHEMBL29426543 | 0.86 | JAK2 (0.39) | ALOX15PIM1PLAUPDPK1JAK2 | |
| SCHEMBL26732575 | 0.86 | JAK2 (0.39) | ALOX15PIM1PLAUPDPK1JAK2 | |
| SCHEMBL23526025 | 0.79 | SOS1 (0.39) | ALOX15PIM1PLAUCASP1ESR2 | |
| SCHEMBL599376 | 0.77 | IDO1 (0.36) | CYP1A2HPGDCYP2C19MEN1KMT2A | |
| SCHEMBL29426477 | 0.75 | ALOX15 (0.35) | ALOX15PIM1PLAUPDPK1JAK2 | |
| SCHEMBL24469239 | 0.74 | POLB (0.36) | ALOX15PIM1PLAUMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261456-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2023-06-13 | — | — | CN | disclosed |