Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 8/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | USP2 | O75604 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252810 | 1.00 | KDM4C (0.47) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL25299117 | 0.85 | CYP1A2 (0.54) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30452132 | 0.84 | KDM4C (0.44) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24252425 | 0.84 | KDM4C (0.44) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30451531 | 0.84 | KDM4C (0.47) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24252799 | 0.84 | KDM4C (0.47) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30452098 | 0.83 | KDM4C (0.46) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24253018 | 0.83 | KDM4C (0.46) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24252447 | 0.83 | HTR1A (0.58) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24252877 | 0.83 | KDM4C (0.45) | KDM4CAPLNRCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463462-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| CN-118715231-A | Complement factor inhibitors and uses thereof | 安尼艾克松股份有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| WO-2023137166-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. (US) | 2023-07-20 | — | — | WO | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |