Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.53 |
| ▸ | PKM | P14618 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017803 | 1.00 | MAPT (0.53) | MAPTPKMPOLBTDP1SMN1; SMN2 | |
| SCHEMBL1700546 | 0.93 | MAPT (0.52) | MAPTPKMPOLBTDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28666327 | 0.92 | MAPT (0.54) | MAPTPKMPOLBTDP1SMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27935409 | 0.84 | MAPT (0.45) | MAPTPKMPOLBTDP1SMN1; SMN2 | |
| SCHEMBL1541487 | 0.83 | MAPT (0.64) | MAPTPKMPOLBTDP1SMN1; SMN2 | |
| SCHEMBL523815 | 0.82 | MAPT (0.59) | MAPTPKMPOLBTDP1SMN1; SMN2 | |
| SCHEMBL1956219 | 0.82 | MAPT (0.56) | MAPTPKMPOLBTDP1SMN1; SMN2 | |
| SCHEMBL1956216 | 0.82 | MAPT (0.56) | MAPTPKMPOLBTDP1SMN1; SMN2 | |
| SCHEMBL29387647 | 0.82 | MAPT (0.59) | MAPTPKMPOLBTDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6092 | 0.81 | CHRM3 (0.41) | MAPTSMN1; SMN2HTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116270660-A | Bcl-2/Bcl-xl inhibitor-containing composition and preparation method and application thereof | 广州麓鹏制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116236583-A | Bcl-2/Bcl-xl inhibitor-containing composition and preparation method and application thereof | 广州麓鹏制药有限公司 | 2023-06-09 | — | — | CN | disclosed |