Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 19/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 19/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 17/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.40 |
| ▸ | TSHR | P16473 | 13/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 12/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 9/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29015440 | 1.00 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL30451463 | 0.94 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL29015354 | 0.94 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL29015416 | 0.94 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL30451585 | 0.94 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL29015672 | 0.88 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL30451923 | 0.88 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL24252333 | 0.87 | NPC1 (0.41) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL30467624 | 0.87 | NPC1 (0.41) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL29015646 | 0.85 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2C19ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |