SCHEMBL30452220

SCHEMBL30452220

Fc1ccc(Sc2ccc(F)cc2F)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
MAPK14 Q16539 10/20 0.45
MAPK13 O15264 1/20 0.41
PTGS2 P35354 3/20 0.41
PTGS1 P23219 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
USP7 Q93009 2/20 0.41
USP10 Q14694 1/20 0.41
USP47 Q96K76 1/20 0.41
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL576377 1.00 ALDH1A1 (0.46) ALDH1A1MAPK14MAPK13PTGS2PTGS1
SCHEMBL3544040 0.87 MAPK14 (0.39) ALDH1A1MAPK14MAPK13PTGS2PTGS1
SCHEMBL576683 0.83 ALDH1A1 (0.46) ALDH1A1MAPK14MAPK13PTGS2PTGS1
SCHEMBL30453204 0.83 ALDH1A1 (0.46) ALDH1A1MAPK14MAPK13PTGS2PTGS1
SCHEMBL777382 0.82 MAPK14 (0.42) ALDH1A1MAPK14MAPK13
SCHEMBL29722938 0.82 MAPK14 (0.42) ALDH1A1MAPK14MAPK13
SCHEMBL1339061 0.82 SLC6A4 (0.51) ALDH1A1
SCHEMBL19042224 0.79 ALDH1A1 (0.48) ALDH1A1MAPK14MAPK13CES2CES1
SCHEMBL576684 0.79 ALDH1A1 (0.42) ALDH1A1MAPK14MAPK13PTGS2PTGS1
SCHEMBL29722916 0.79 ALDH1A1 (0.42) ALDH1A1MAPK14MAPK13PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115911573-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2023-04-04 CN disclosed